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Wednesday, April 18, 2018

EnCor CEO Jerry Shaw (a SMBI graduate company) peers through a ...
src: sidmartinbio.org

EnCor Biotechnology is a United States company that manufactures antibodies to neural and yeast proteins. Founded in 1999 as a spin-off from the University of Florida by Dr. Gerry Shaw, a British scientist and professor at the University of Florida, the company is based in Gainesville, Florida and markets antibody reagents originally made for research purposes, but which also have commercial value.


Video EnCor Biotechnology



History

EnCor Biotechnology was formed in at the end of 1999 to market antibody reagents originally made for research purposes, but which also had some commercial potential. Three years later EnCor moved into rented lab space at the Sid Martin Biotechnology Incubator, a facility dedicated to commercialization of intellectual property generated in the University of Florida. The company quickly become profitable and, in 2006, relocated to new premises in Gainesville.

In 2005, EnCor began collaborating with basic scientists and clinicians to produce articles in peer reviewed scientific publications focused on the examination of various plasma, serum and CSF biomarkers of nervous system damage and degeneration. One of these is the phosphorylated, axonal form of the major neurofilament protein heavy chain protein which has the HGNC name NEFH, though is usually referred to as pNF-H in the scientific literature. Two further studies describe novel EnCor assays for UCHL1 and alpha-synuclein, two major brain proteins implicated in the development of Parkinson's and other neurological diseases.

By 2012, EnCor product line had increased to almost 100 products, the antibodies mostly being used for research purposes, with a particular focus on immunocytochemistry and western blotting, though many are also utilized for immunoprecipitation and ELISA. Some have become useful for diagnostic histopathology and for monitoring the levels of protein biomarkers, of research and potential clinical utility. EnCor supplies reagents to research labs and other reagent companies such as Abcam, Covance, Invitrogen, Millipore Corporation, and Novus Biologicals.


Maps EnCor Biotechnology



Publications

  • Shaw G, Yang C, Ellis R, Anderson K, Parker Mickle J, Scheff S, Pike B, Anderson DK, Howland DR (Nov 2005). "Hyperphosphorylated neurofilament NF-H is a serum biomarker of axonal injury". Biochem. Biophys. Res. Commun. 336 (4): 1268-1277. doi:10.1016/j.bbrc.2005.08.252. PMID 16176808. 

Mouse 3H11 NF-M Antibody from EnCor Biotechnology Inc.
src: www.encorbio.com


References

  • Article about University of Florida start up companies from Business Week, 2007
  • Gainesville Sun article about one of EnCor's discoveries, 2005

Chicken Antibody to GFAP from EnCor #1
src: www.encorbio.com


External links

  • Official website

Source of the article : Wikipedia

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